GENERAL CATALOGUE
STAT3-IN-11
HY-149007 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-149007
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Manufacturer product page
medchemexpress.com/stat3-in-11.htmlCatalog No: HY-149007
CAS No: 2503096-50-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
STAT3-IN-11 7a is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes Survivin and Mcl-1 without affecting its upstream tyrosine kinases Src and JAK2 levels and p-STAT1 expression. STAT3-IN-11 can induce cancer cell apoptosis, which is potential for the discovery of effective STAT3 inhibitors and antitumor agents against cancers.
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