

HY-155808 · 50 mg
MedChemExpress · Cat: HY-155808
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medchemexpress.com/stat3-in-18.htmlDescription
STAT3-IN-18 compound SPP is a platinum IV complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer BC cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo.







