GENERAL CATALOGUE
STAT3-IN-20
HY-155982 · 5 mg
MedChemExpress · Cat: HY-155982
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medchemexpress.com/stat3-in-20.htmlCatalog No: HY-155982
CAS No: 2768427-54-7
Category: JAK STAT Signaling
Pack Size: 5 mg
Brand: MedChemExpress
Description
STAT3-IN-20 Compound 40 is a selective STAT3 inhibitor IC50: 0.65 ?M . STAT3-IN-20 binds the SH2 domain to inhibit STAT3 phosphorylation, translocation, and downstream gene transcription. STAT3-IN-20 exhibits antiproliferative activities against STAT3-overactivated DU145 and MDA-MB-231 cancer cells IC50: 2.97 ?M and 3.26 ?M respectively . STAT3-IN-20 induces cell cycle arrest and apoptosis.
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