GENERAL CATALOGUE
STF-1084
HY-141831 · 5 mg
MedChemExpress · Cat: HY-141831
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Catalog No: HY-141831
CAS No: 2298390-71-1
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
STF-1084 is a specific, cell-impermeable, competitive inhibitor of ENPP1 Ki = 33 nM . STF-1084 increases extracellular cGAMP concentrations by preventing its degradation by ENPP1, thereby enhancing immune infiltration. STF-1084 acts synergistically with ionizing radiation IR and cGAMP to delay tumor progression. STF-1084 can be used to study cancers with low immunogenicity.
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