

HY-124586 · 500 g
MedChemExpress · Cat: HY-124586
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medchemexpress.com/Streptonigrin.htmlDescription
Streptonigrin Bruneomycin is an orally active antibiotic and pan-PAD inhibitor, inhibiting PAD1, PAD2, PAD3 and PAD4 with IC50 of 48.3 ?M, 26.1 ?M, 0.43 ?M and 2.5 ?M, respectively. Streptonigrin inhibits SENP1 IC50 of 0.518 ?M and reduces HIF1?. Streptonigrin increases p53 and Apoptosis. Streptonigrin shows antiviral activity against Rauscher murine leukemia virus. Streptonigrin has immunosuppressive effects. Streptonigrin has antitumor activity against osteosarcoma.







