GENERAL CATALOGUE
SU-11752
HY-114923 · 50 mg
MedChemExpress · Cat: HY-114923
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Catalog No: HY-114923
CAS No: 688036-19-3
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
SU-11752 is an inhibitor for DNA-dependent protein kinase DNA-PK with an IC50 of 0.13 ?M. SU-11752 inhibits PI3K p110? kinase with IC50 of 1.1 ?M. SU-11752 binds competitively for ATP-site in DNA-PK, results in inhibition of intracellular DNA double-strand break repair and increases the sensitivity of cells to radiotherapy.