Suramin sodium salt

Description

Suramin sodium salt Suramin hexasodium salt is a reversible and competitive protein-tyrosine phosphatases PTPases inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 IC50=297 nM , SirT2 IC50=1.15 ?M , and SirT5 IC50=22 ?M . Suramin sodium salt is a competitive inhibitor of reverse transcriptase DNA topoisomerase II: IC50=5 ?M . Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase RdRp inhibitor. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent.