GENERAL CATALOGUE
Surfen dihydrochloride
HY-122704A · 10 mM * 1 mL in Water
MedChemExpress · Cat: HY-122704A
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Catalog No: HY-122704A
CAS No: 5424-37-3
Category: Anti-infection
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress
Description
Surfen dihydrochloride is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen dihydrochloride inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 ?M. Surfen dihydrochloride inhibits HSV-1 viral infection. Surfen dihydrochloride inhibits neural differentiation, delays remyelination, and alleviates EAE.
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