

HY-138293 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138293
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medchemexpress.com/cdk7-in-3.htmlDescription
SY-5609 CDK7-IN-3 is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 Ki=2600 nM , CDK9 Ki=960 nM , CDK12 Ki=870 nM . SY-5609 induces apoptosis in tumor cells and has antitumor activity.