GENERAL CATALOGUE
SZM679
HY-151873 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-151873
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Catalog No: HY-151873
CAS No: 3027645-52-6
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SZM679 is a potent, orally active and selective RIPK1 inhibitor with Kd values of 8.6 nM and >5000 nM for RIPK1 and RIPK3, respectively. SZM679 reverses the tumor necrosis factor-induced systemic inflammatory response. SZM679 decreases the Tau hyperphosphorylation, neuroinflammation, and the RIPK1 phosphorylation level in the hippocampus and cortex. SZM679 can be used in research of Alzheimers disease AD .
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