GENERAL CATALOGUE
T0901317
HY-10626 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10626
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medchemexpress.com/T0901317.html
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Catalog No: HY-10626
CAS No: 293754-55-9
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXR?. T0901317 activates FXR with an EC50 of 5 ?M. T0901317 is ROR? and ROR? dual inverse agonist with Ki values of 132 nM and 51 nM, respectively. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein LDL receptor-deficient mice.
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