TAB2 Mouse Monoclonal Antibody

Description

EnkiLife offers the TAB2 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ELISA,FC application. Alternative Names of Immunogen: CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Research Area: MAPK signaling pathway