GENERAL CATALOGUE
Taccalonolide A
HY-N2416 · 5 mg
MedChemExpress · Cat: HY-N2416
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medchemexpress.com/taccalonolide-a.html
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Catalog No: HY-N2416
CAS No: 108885-68-3
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein Pgp and multidrug resistance protein 7 MRP7 , with an IC50 of 622 nM for SK-OV-3 cells.
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