GENERAL CATALOGUE
TAK-285
HY-15196 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15196
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medchemexpress.com/TAK-285.html
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Catalog No: HY-15196
CAS No: 871026-44-7
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR HER1 inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity. TAK-285 can cross the blood-brain barrier BBB .
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