GENERAL CATALOGUE
TAK-683 acetate
HY-P2161B · 1 mg
MedChemExpress · Cat: HY-P2161B
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Catalog No: HY-P2161B
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
TAK-683 acetate is a potent full KISS1 receptor KISS1R agonist IC50=170 pM with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively. TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer.
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