GENERAL CATALOGUE
TAK-960
HY-15160 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15160
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medchemexpress.com/TAK-960.html
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Catalog No: HY-15160
CAS No: 1137868-52-0
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
TAK-960 is an orally available, selective inhibitor of polo-like kinase 1 PLK1 , with an IC50 of 0.8 nM. TAK-960 also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.
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