GENERAL CATALOGUE
TAK-960 hydrochloride
HY-15160A · 50 mg
MedChemExpress · Cat: HY-15160A
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medchemexpress.com/TAK-960-hydrochloride.htmlCatalog No: HY-15160A
CAS No: 1137868-96-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
TAK-960 hydrochloride is an orally available, selective inhibitor of polo-like kinase 1 PLK1 , with an IC50 of 0.8 nM. TAK-960 hydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 hydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.