GENERAL CATALOGUE
Takeda-6D
HY-18318 · 1 mg
MedChemExpress · Cat: HY-18318
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medchemexpress.com/takeda-6d.htmlCatalog No: HY-18318
CAS No: 1125632-93-0
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
Takeda-6D compound 6d is an orally active and potent BRAF/VEGFR2 inhibitor, with IC50 values of 7.0 and 2.2 nM, respectively. Takeda-6D shows antiangiogenesis by suppressing the VEGFR2 pathway in 293/KDR and VEGF-stimulated HUVEC cells.Takeda-6D shows significant suppression of ERK1/2 phosphorylation. Takeda-6D shows antitumor activity.
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