GENERAL CATALOGUE
Talaroconvolutin A
HY-N15742 · 50 mg
MedChemExpress · Cat: HY-N15742
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Catalog No: HY-N15742
CAS No: 273199-42-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Talaroconvolutin A is a ferroptosis inducer. Talaroconvolutin A induces ferroptosis by increasing reactive oxygen species ROS levels rather than the GPX4 pathway. Talaroconvolutin A downregulates the expression of the channel protein solute carrier family 7 member 11 SLC7A11 and upregulates arachidonic acid lipoxygenase 3 ALOXE3 . Talaroconvolutin A inhibits the growth of colorectal cancer cells HCT116 and bladder cancer cells SW480 with IC50 values of 1.22 ?M and 1.4 ?M, respectively. Talaroconvolutin A can be used in the study of colorectal cancer and bladder cancer 1 2 3 .
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