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Talfirastide acetate
GENERAL CATALOGUE

Talfirastide acetate

HY-12403A · 10 mM * 1 mL in Water

MedChemExpress · Cat: HY-12403A

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Catalog No: HY-12403A
CAS No: 2855063-75-9
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress

Description

Angiotensin 1-7 Ang- 1-7 acetate is an endogenous heptapeptide from the renin-angiotensin system RAS with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity IC50=0.65 ?M . Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium.

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