Talfirastide (Standard)

Description

Talfirastide Standard is the analytical standard of Talfirastide. This product is intended for research and analytical applications. Angiotensin 1-7 Ang- 1-7 is an endogenous heptapeptide from the renin-angiotensin system RAS with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity IC50=0.65 ?M . Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .