GENERAL CATALOGUE
Taminadenant
HY-109139 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-109139
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Catalog No: HY-109139
CAS No: 1337962-47-6
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Taminadenant NIR178; PBF509 is a highly potent and orally active adenosine A2A receptor A2AR antagonist. Taminadenant can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with KB values of 72.8 nM and 8.2 nM, respectively. Taminadenant reverses motor impairments in several rat models of movement disorders, including catalepsy, tremor, and hemiparkinsonism. Taminadenant can also inhibit tumor growth when combined with Spartalizumab HY-P9972 . Taminadenant reactivate the antitumor immune response.
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