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Tanespimycin-d5
GENERAL CATALOGUE

Tanespimycin-d5

HY-10211S · 50 mg

MedChemExpress · Cat: HY-10211S

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Catalog No: HY-10211S
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

Tanespimycin-d5 17-AAG-d5; NSC 330507-d5; CP 127374-d5 is the deuterium labeled Tanespimycin HY-10211 . Tanespimycin 17-AAG is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.

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