GENERAL CATALOGUE
Tanespimycin
HY-10211 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10211
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medchemexpress.com/17-AAG.html
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Catalog No: HY-10211
CAS No: 75747-14-7
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Tanespimycin 17-AAG is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.
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