

HY-10211R · 5 mg
MedChemExpress · Cat: HY-10211R
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medchemexpress.com/tanespimycin-standard.htmlDescription
Tanespimycin Standard is the analytical standard of Tanespimycin. This product is intended for research and analytical applications. Tanespimycin 17-AAG is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.