GENERAL CATALOGUE
Taspoglutide acetate
HY-P0165B · 1 mg
MedChemExpress · Cat: HY-P0165B
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medchemexpress.com/taspoglutide-acetate.htmlCatalog No: HY-P0165B
CAS No: 1022150-16-8
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
Taspoglutide R1583 acetate is an agonist of the glucagon-like peptide 1 receptor GLP-1R with an Ki value of 1.1 nM. Taspoglutide acetate induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R EC50 = 0.06 nM . Taspoglutide acetate decreases blood levels of glucose and increases blood levels of insulin in a glucose tolerance test in Zucker diabetic obese rats. Taspoglutide acetate reduces blood levels of gastric inhibitory polypeptide GIP , plasma levels of triglycerides, and body weight in the same model.
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