GENERAL CATALOGUE
Tat-NR2B9c TFA
HY-P0117A · 5 mg
MedChemExpress · Cat: HY-P0117A
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medchemexpress.com/tat-nr2b9c-tfa.htmlCatalog No: HY-P0117A
CAS No: 1834571-04-8
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
Tat-NR2B9c TFA Tat-NR2Bct TFA is a postsynaptic density-95 PSD-95 inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 PSD-95 PDZ domain 2 and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 ?M and 8 ?M, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase nNOS /PSD-95 interaction, and possesses neuroprotective efficacy.