

HY-19750 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19750
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Manufacturer product page
medchemexpress.com/DprE1-IN-1.html
Description
TBA-7371 is an orally active and non-covalent inhibitor of Decaprenylphosphoryl-?-D-ribose oxidase DprE1 of Mycobacterium tuberculosis MIC=0.64 ?g/mL . TBA-7371 can block the synthesis of arabinose in the bacterial cell wall, resulting in cell wall structural defects, thereby exerting an anti-tuberculosis effect. TBA-7371 can be used in the research of anti-tuberculosis drugs and has a synergistic bactericidal effect with Bedaquiline HY-14881 and other drugs.







