

HY-14562 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14562
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medchemexpress.com/TBPB.htmlDescription
TBPB tert-butyl peroxybenzoate is a highly selective, blood-brain-permeable M1 mAChR allosteric agonist EC50=289 nM with anti-schizophrenia and anti-inflammatory activities. TBPB can enhance the sensitivity of M1 receptors to acetylcholine, activate downstream signaling pathways, and inhibit the release of pro-inflammatory cytokines TNF-?, IL-6 . TBPB can regulate the processing of amyloid and can be used in the study of neurodegenerative diseases such as Alzheimers disease and inflammation-related diseases such as sepsis .