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TC-E 5008
GENERAL CATALOGUE

TC-E 5008

HY-110144 · 50 mg

MedChemExpress · Cat: HY-110144

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medchemexpress.com/tc-e-5008.html
Catalog No: HY-110144
CAS No: 50405-58-8
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

TC-E 5008 is a potent mutant IDH1 inhibitor with Ki values of 190 nM and 120 nM for R132H and R132C IDH1 mutants, respectively. TC-E 5008 exhibits very weak activity against WT-IDH1 with a Ki value of 12.3 ?M. TC-E 5008 has anti-proliferative activity on multiple ER positive breast cancer cell lines.

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