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TD-428
GENERAL CATALOGUE

TD-428

HY-114407 · 5 mg

MedChemExpress · Cat: HY-114407

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medchemexpress.com/TD-428.html
Catalog No: HY-114407
CAS No: 2334525-50-5
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress

Description

TD-428 is a PROTAC connected by ligands for Cereblon and BRD4. TD-428 is a highly specific BRD4 degrader with a DC50 of 0.32 nM. TD-428 is a BET PROTAC, which comprises TD-106 a CRBN ligand linked to JQ1 a BET inhibitor . TD-428 efficiently induce BET protein degradation.

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