GENERAL CATALOGUE
TD034
HY-176542 · 1 mg
MedChemExpress · Cat: HY-176542
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Catalog No: HY-176542
CAS No: 3030718-42-1
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
TD034 is a selective, reversible and noncovalent HDAC11 inhibitor with an IC50 of 5.1 nM and a Ki of 1.5 nM. TD034 does not inhibit other HDACs or sirtuins. TD034 inhibits the defatty acylation of SHMT2 HDAC11 substrate . TD034 decreases the YAP1 level via HDAC11 inhibition. TD034 can be used for the study of lung cancer.
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