GENERAL CATALOGUE
TDP-665759
HY-18329 · 50 mg
MedChemExpress · Cat: HY-18329
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medchemexpress.com/tdp-665759.htmlCatalog No: HY-18329
CAS No: 787632-66-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
TDP-665759 is an inhibitor for HDm2:p53 complex, and thus activates p53, inhibits STAT3 signaling pathway EC50 of 5.90 ?M and the cell viability of p53 expressing A549R IC50 of 7.02 ?M . TDP-665759 induces apoptosis in HepG2. TDP-665759 exhibits antitumor efficacy in mouse models.
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