GENERAL CATALOGUE
Teduglutide TFA
HY-P1624A · 50 mg
MedChemExpress · Cat: HY-P1624A
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medchemexpress.com/teduglutide-tfa.html
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Catalog No: HY-P1624A
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 GLP-2 analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 NR4a1 /nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis.
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