GENERAL CATALOGUE
Tegaserod maleate
HY-14153A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-14153A
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medchemexpress.com/Tegaserod-maleate.htmlCatalog No: HY-14153A
CAS No: 189188-57-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Tegaserod maleate SDZ-HTF-919 is an orally active serotonin receptor 4 HTR4; 5-HT4R agonist and a 5-HT2B receptor antagonist. Tegaserod maleate has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome IBS research.
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