GENERAL CATALOGUE
Telaglenastat (Standard)
HY-12248R · 5 mg
MedChemExpress · Cat: HY-12248R
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medchemexpress.com/telaglenastat-standard.htmlCatalog No: HY-12248R
CAS No: 1439399-58-2
Category: Autophagy
Pack Size: 5 mg
Brand: MedChemExpress
Description
Telaglenastat Standard is the analytical standard of Telaglenastat. This product is intended for research and analytical applications. Telaglenastat CB-839 is a first-in-class, selective, reversible and orally active glutaminase 1 GLS1 inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA kidney-type glutaminase and GAC glutaminase C compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity.
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