GENERAL CATALOGUE
Tepotinib
HY-14721 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14721
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medchemexpress.com/EMD-1214063.html
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Catalog No: HY-14721
CAS No: 1100598-32-0
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Tepotinib EMD-1214063 is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects.
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