GENERAL CATALOGUE
Tepotinib hydrochloride
HY-14721A · 50 mg
MedChemExpress · Cat: HY-14721A
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medchemexpress.com/tepotinib-hydrochloride.htmlCatalog No: HY-14721A
CAS No: 1103508-80-0
Category: Autophagy
Pack Size: 50 mg
Brand: MedChemExpress
Description
Tepotinib EMD-1214063 hydrochloride is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib hydrochloride inhibits c-Met phosphorylation and induces autophagy. Tepotinib hydrochloride has antitumor effects.