GENERAL CATALOGUE
Terfenadine-d3
HY-B1193S · 2 mg
MedChemExpress · Cat: HY-B1193S
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Catalog No: HY-B1193S
CAS No: 192584-82-0
Category: Apoptosis
Pack Size: 2 mg
Brand: MedChemExpress
Description
Terfenadine-d3 AAasAasAA+/- -Terfenadine-d3 is the deuterium labeled Terfenadine. Terfenadine AAasAasAA+/- -Terfenadine is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 2 .
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