GENERAL CATALOGUE
Terfenadine
HY-B1193 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B1193
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Manufacturer product page
medchemexpress.com/Terfenadine.htmlCatalog No: HY-B1193
CAS No: 50679-08-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Terfenadine AAasAasAA+/- -Terfenadine is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
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