GENERAL CATALOGUE
Tesevatinib (Standard)
HY-13314R · 50 mg
MedChemExpress · Cat: HY-13314R
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Manufacturer product page
medchemexpress.com/tesevatinib-standard.htmlCatalog No: HY-13314R
CAS No: 781613-23-8
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
Tesevatinib Standard is the analytical standard of Tesevatinib. This product is intended for research and analytical applications. Tesevatinib XL-647 is an orally available, blood-brain barrier-penetrant inhibitor of the epidermal growth factor receptor EGFR . Tesevatinib significantly reduces cellular viability, with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Tesevatinib also inhibits HER2 IC50=16.1 nM , VEGFR2 IC50=1.5 nM , and Src IC50=10.3 nM . Tesevatinib can inhibit tumor proliferation and exhibits antitumor activity.
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