GENERAL CATALOGUE
Tesirine
HY-128952 · 1 mg
MedChemExpress · Cat: HY-128952
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medchemexpress.com/mp-peg8-va-pabc.htmlCatalog No: HY-128952
CAS No: 1595275-62-9
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress
Description
Tesirine SG3249 is an antibody-drug conjugate ADC pyrrolobenzodiazepine PBD dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 HY-101161 is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity.
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