GENERAL CATALOGUE
TFGF-18
HY-171031 · 50 mg
MedChemExpress · Cat: HY-171031
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medchemexpress.com/tfgf-18.html
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Catalog No: HY-171031
CAS No: 2222662-20-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
TFGF-18 is a GSK-3? inhibitor IC50: 0.59 ?M . TFGF-18 inhibits LPS-induced microglia activation and proinflammatory mediators release via inhibiting GSK-3? and downstream p65/NF-?B signaling. TFGF-18 inhibits neuronal apoptosis and oxidative stress, inhibits expressions of Bax, caspase3 and cleaved-caspase3 and increases the expression of Bcl-2. TFGF-18 has neuroprotection effect, inhibit neuroinflammation and attenuates cognitive impairment.
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