GENERAL CATALOGUE
TfR-1-IN-1
HY-159569 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-159569
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Catalog No: HY-159569
CAS No: 1643444-62-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
TfR-1-IN-1 compound C4 is an inhibitor of transferrin receptor 1 TfR-1 with anticancer activity. TfR-1-IN-1 strongly increases intracellular iron II levels as a driving force for the induction of ferroptosis. TfR-1-IN-1 significantly reduces the metabolic activity of ovarian cancer A2780cis , breast cancer MDA-MB 231 , and leukemia HL-60 cell lines with IC50 values of 0.51, 0.46, and 0.48 ?M, respectively.
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