GENERAL CATALOGUE
TH1760
HY-139193 · 5 mg
MedChemExpress · Cat: HY-139193
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Catalog No: HY-139193
CAS No: 2567914-01-4
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
TH1760 is an inhibitor of NUDIX-type 15 NUDT15 with an IC50 value of 25 nM. TH1760 sensitizes cells to 6-thioguanine by enhancing the accumulation of 6-thio- d GTP in nucleic acids. TH1760 enhances the anti-leukemia effect of thiopurine.
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