GENERAL CATALOGUE
TH287 hydrochloride
HY-16965A · 50 mg
MedChemExpress · Cat: HY-16965A
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medchemexpress.com/TH287-hydrochloride.htmlCatalog No: HY-16965A
CAS No: 1638211-05-8
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
TH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 ?M. TH287 hydrochloride could act as a chemotherapeutic agent for cancer research.
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