GENERAL CATALOGUE
Thalidomide-5-propargyl
HY-W457950 · 25 mg
MedChemExpress · Cat: HY-W457950
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medchemexpress.com/thalidomide-5-propargyl.htmlCatalog No: HY-W457950
CAS No: 2226303-74-6
Category: Apoptosis
Pack Size: 25 mg
Brand: MedChemExpress
Description
Thalidomide-5-propargyl is a propargyl-modified Thalidomide HY-14658 , that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-5-propargyl use alkynyl group at the end to be directly used in the synthesis of triazoles in the synthesis of PROTAC molecules, and is a key intermediate in the synthesis of PROTAC molecules based on CRBN design.