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Thalidomide-NH-PEG3-NH-Boc
GENERAL CATALOGUE

Thalidomide-NH-PEG3-NH-Boc

HY-44063 · 5 mg

MedChemExpress · Cat: HY-44063

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Catalog No: HY-44063
CAS No: 2204246-03-5
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

Thalidomide-NH-PEG3-NH-Boc is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide HY-14658 and NH-PEG3-NH-Boc. Thalidomide-NH-PEG3-NH-Boc acts as a ligand for Cereblon to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-PEG3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-PEG3-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

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