GENERAL CATALOGUE
Theaflavin-3-gallate
HY-N0245 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0245
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medchemexpress.com/theaflavin-3-gallate.htmlCatalog No: HY-N0245
CAS No: 30462-34-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione GSH in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway.