GENERAL CATALOGUE
Thianthrene
HY-W014120 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W014120
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medchemexpress.com/thianthrene.htmlCatalog No: HY-W014120
CAS No: 92-85-3
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 PTR1 . Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani IC50 = 23 ?M . Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo.
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